Whether you're looking to be treated, or just want a second opinion, Nebraska Medicine offers matches you up with a world-renowned lymphoma team.

We treat all the forms of lymphoma, which is a cancer that starts in white blood cells called lymphocytes. Lymphocytes are part of the immune system.

The two main types are Hodgkin lymphoma and non-Hodgkin lymphoma (NHL).

Hodgkin lymphoma has unique cell characteristics that distinguish it from non-Hodgkin lymphoma, called the Reed-Sternberg cells.

Non-Hodgkin lymphoma represents a diverse group of diseases distinguished by the characteristics of the cancer cells associated with each disease type. Most people with NHL have a B-cell type of NHL (about 85 percent). The others have a T-cell type or an NK-cell type of lymphoma.

Non-Hodgkin Lymphoma

The cancer typically develops in the lymphatic system from cells called lymphocytes, white blood cells that battle infections. This kind of cancer develops in places like the lymph nodes, bone marrow, spleen, thymus or digestive tract.

If you have cancer, there's a good chance it's non-Hodgkin, which people can get at any point in your life but generally skews older. Between 60,000 and 70,000 people per year get one of more than 60 different types of non-Hodgkin's lymphoma, of which diffuse large B-cell is the most common.

What you want to figure out first is whether the non-Hodgkin lymphoma you have grows slowly (indolent) or fast (aggressive). Treatments for the aggressive lymphomas typically start immediately, and many forms can be cured. With the slower growing lymphoma types, treatment may not be immediately necessary.

Non-Hodgkin Lymphoma:

  • Burkitt lymphoma
  • Chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Diffuse large B-cell lymphoma
  • Follicular lymphoma
  • Mantle cell lymphoma
  • Hairy cell leukemia
  • Marginal zone B-cell lymphomas
  • Lymphoplasmacytic lymphoma (Waldenstrom's macroglobulinemia)
  • Primary effusion lymphoma
  • Primary central nervous system (CNS) lymphoma
  • Precursor T-lymphoblastic lymphoma/leukemia
  • Mycosis fungoides
  • Sezary syndrome
  • Lymphomatoid papulosis
  • Subcutaneous panniculitis-like T-cell lymphoma
  • Primary cutaneous peripheral T-cell lymphomas, unspecified
  • Anaplastic large cell lymphomas, primary cutaneous type and systemic type
  • Peripheral T-cell lymphoma, not otherwise specified
  • Angioimmunoblastic T-cell lymphoma
  • Adult T-cell lymphoma/leukemia
  • Extranodal NK/T-cell lymphoma, nasal type
  • Enteropathy-associated T-cell lymphoma
  • Gamma/delta hepatosplenic T-cell lymphoma

Hodgkin Lymphoma

Hodgkin lymphoma is the other type of lymphoma, and impacts on average 9,000 people each year, and is most commonly primarily those in their mid to late 20s or elderly.

Hodgkin’s Lymphoma:

  • Classical Hodgkin lymphoma
  • Nodular sclerosis Hodgkin lymphoma
  • Mixed cellularity Hodgkin lymphoma
  • Lymphocyte-depleted Hodgkin lymphoma
  • Lymphocyte-rich classic Hodgkin lymphoma
  • Nodular lymphocyte-predominate Hodgkin lymphoma

Service Options

Patient Guides

The Highest Level of Treatment Methods

Our world renowned team works with you to choose the best possible care plan tailored to meet your needs. This may include:


There are many types of lymphomas and each requires a customized treatment plan. We have a team of cancer doctors completely dedicated to lymphoma care and treatment. This ensures you will receive care from a team of experts who are familiar with the latest treatments and advancements and can apply them to your case. Our lymphoma team averages 150 to 160 bone and blood marrow transplants a year and have performed more than 4,800 transplants since the program's founding.

World Class Ground-Breaking Advancements

Doctors and researchers at Nebraska Medicine have been pioneers in the field and are recognized internationally for a number of ground-breaking advancements. This includes the study and introduction of autologous transplantation which uses a patient’s own stem cells to reduce rejection issues. Our innovative treatments have helped improve success rates and have made blood and marrow transplants a more viable and promising option for a growing number of patients. In fact, doctors from around the world call upon Nebraska Medicine’s lymphoma team for consultation.

Expertise Near You

The Nebraska Lymphoma Study Group (NLSG) brings community oncologists, pathologists and their counterparts together to provide the very best in lymphoma treatment to patients with Hodgkin disease, non-Hodgkin lymphoma and other neoplastic hematologic disorders. You have the opportunity to stay in your hometown to receive state-of-the-art treatment while having access to the expertise and resources of an academic health sciences center. Nearly 6,500 patients have been treated and more than 65,000 biopsies reviewed since the study group was formed in 1982.

Nationally Ranked

U.S. News & World Report has ranked Nebraska Medicine as one of the best cancer centers for several years. We are also a National Comprehensive Cancer Network member, which means we are part of an alliance of the nation’s leading cancer centers that focuses on improving patient care. As a National Cancer Institute-designated Cancer Center, Nebraska Medicine is known for its clinical trials and ground-breaking research.

A Team Approach

With the many different types of lymphoma, it is imperative that your cancer be properly identified so doctors can formulate the best treatment plan for you. To precisely diagnose your cancer, our hematopathologists - who are sought after nationally for their expertise - will carefully determine your specific type of lymphoma. A team of doctors, that may include medical oncologists, pathologists, radiation oncologists, surgical oncologists, as well as other specialists in infectious disease and palliative care, meet regularly to discuss your case and develop a coordinated plan of care. Patients undergoing cancer treatment at Nebraska Medicine also have access to our 24/7 Infusion Center at the Peggy D. Cowdery Patient Care Center, which serves as both a treatment center and 24/7 urgent-care-type facility. A rare offering in the region.

Clinical Trials

Access to clinical trials affords patients the ability to participate in leading edge treatments that otherwise would not be available to them. You may qualify to participate in our latest lymphoma clinical trials, which may involve new drug options, chemotherapy treatments as well as radiation therapy. The latest discoveries made in research laboratories are worked into comprehensive lymphoma treatment plans, improving success rates. See what clinical trials related to lymphomas are going on right now. Talk to your care team to see if there are clinical trials you may qualify for.

Nebraska Medicine is also part of the National Institutes of Health/National Cancer Institute Bone Marrow Transplant Clinical Trials Network – a consortium transplant centers across the country that collaborate on clinical trials to derive data from a larger population of patients and to allow for greater sharing of information between centers. Through this network, doctors can study and refine their techniques to diagnose, treat and follow patients to provide them with optimal care.

For Academic Inquiries Call 402.559.8500