cancer clinical trials for GI (ONC)

21 GI (ONC) clinical trials found. View a list of all cancer clinical trial types.

• A Randomized Phase II Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy with and without BMX-001 as part of Total Neoadjuvant Therapy in Patients with Newly Diagnosed Locally Advanced Rectal Adenocarcinoma

  Current Status: Open

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• A Pilot Study of Chemoprevention With Tamoxifen in Patients With Pre-Invasive Pancreas Mucinous Cystic Neoplasms Who Will Not Undergo Immediate Resection

  Current Status: Open

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• Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

  Current Status: Open

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• Pancreatic Cancer Early Detection Consortium (PRECEDE)

  Current Status: Open

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• Randomized Phase III Trial of mFOLFIRINOX +/- Nivolumab vs. FOLFOX +/- Nivolumab for First-Line Treatment of Metastatic HER2-Negative Gastroesophageal Adenocarcinoma

  Current Status: Open

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• A Pragmatic Randomized Phase III Trial Evaluating Total Ablative Therapy for Patients with Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur)

  Current Status: Open

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• Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)

  Current Status: Open

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• A Phase II Study of Two Doses of Leronlimab (Pro 140) in Combination with Trifluridine + Tipiracil (TAS-102) + Bevacizumab in Participants with CCR5+, Microsatellite Stable (MSS), Relapsed Refractory Metastatic Colorectal Cancer (mCRC)

  Current Status: Open

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• A Platform Study of RAS(ON) Inhibitors in Patients with Gastrointestinal Solid Tumors

  Current Status: Not Open

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• A Phase II, Open-Label, Multicenter, Randomized Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Patients With Resected Pancreatic Ductal Adenocarcinoma

  Current Status: Open

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• Radiation Therapy for High-Risk Asymptomatic Bone Metastases: A Pragmatic Multicenter Randomized Phase 3 Clinical Trial (PREEMPT)

  Current Status: Open

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• PCCE Clinical Data and Specimen Repository for Malignant and Non-Malignant Diseases of the Pancreas

  Current Status: Open

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• A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)

  Current Status: Open

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• Targeted Agent and Profiling Utilization Registry (TAPUR) Study

  Current Status: Open

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• A Phase Ib/II Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 193 in Combination with other Therapies in Subjects with Advanced Gastrointestinal, Biliary Tract or Pancreatic cancers with homozygous MTAP deletion

  Current Status: Open

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• ESTABLISHMENT OF A NATIONAL BIOREPOSITORY TO ADVANCE STUDIES OF IMMUNE-RELATED ADVERSE EVENTS

  Current Status: Open

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• Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

  Current Status: Open

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• TIGeR-PaC: Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine plus Nab-Paclitaxel following Induction with sequential IV Gemcitabine plus Nab-Paclitaxel and Radiotherapy for Unresectable Locally Advanced Pancreatic Cancer

  Current Status: Open

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• A Randomized Study Evaluating GLIADEL Compared to Stereotactic Radiosurgery in Patients with Metastatic Brain Disease

  Current Status: Open

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• A Phase I, Dose Escalation and Dose Expansion, Safety and Tolerability Study of onCARlytics (CF33-CD19), Administered Intravenously or Intratumorally in Combination with Blinatumomab in Adults with Advanced or Metastatic Solid Tumors

  Current Status: Not Open

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• An Observational Study Associating Adiponectin Signaling with Acute and Chronic Toxicity Following Pelvic Radiation

  Current Status: Open

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