cancer clinical trials for GI (ONC)

27 GI (ONC) clinical trials found. View a list of all cancer clinical trial types.

• A Randomized, Phase III Study of Rilvegostomig in Combination with Fluoropyrimidine and Trastuzumab Deruxtecan versus Trastuzumab, Chemotherapy, and Pembrolizumab for the First-line Treatment of HER2-positive Gastric Cancer (ARTEMIDE-Gastric01)

  Current Status: Open

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• A Randomized Phase II Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy with and without BMX-001 as part of Total Neoadjuvant Therapy in Patients with Newly Diagnosed Locally Advanced Rectal Adenocarcinoma

  Current Status: Open

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• Researching the Effects of Survivorship, Inflammation, and Neuro-Cognitive Enhancement through Cancer and Eating: The RESILIENCE Study

  Current Status: Open

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• A Pilot Study of Chemoprevention With Tamoxifen in Patients With Pre-Invasive Pancreas Mucinous Cystic Neoplasms Who Will Not Undergo Immediate Resection

  Current Status: Open

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• RASolute 304: A Phase III Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib versus Observation Following Curative Intent Therapy in Patients with Resected Pancreatic Ductal Adenocarcinoma (PDAC)

  Current Status: Open

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• Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

  Current Status: Open

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• ROSETTA CRC-203: A Blinded, Randomized Phase II/III Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

  Current Status: Open

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• The ROSE Study - Research On Survivorship Experiences. Disparities in cancer-related outcomes between rural and non-rural cancer survivors in the catchment areas of the Big 10 Cancer Research Consortium's Population Science Working Group

  Current Status: Open

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• Phase III Randomized Trial of IO-Based Systemic Treatment +/- Liver SBRT in Hepatocellular Cancer With Macrovascular Invasion (HELIO-RT)

  Current Status: Open

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• Pancreatic Cancer Early Detection Consortium (PRECEDE)

  Current Status: Open

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• Randomized Phase III Trial of mFOLFIRINOX +/- Nivolumab vs. FOLFOX +/- Nivolumab for First-Line Treatment of Metastatic HER2-Negative Gastroesophageal Adenocarcinoma

  Current Status: Open

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• A Pragmatic Randomized Phase II Trial Evaluating Total Ablative Therapy for Patients with Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur)

  Current Status: Open

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• Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)

  Current Status: Open

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• A Platform Study of RAS(ON) Inhibitors in Patients with Gastrointestinal Solid Tumors

  Current Status: Open

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• Longitudinal pilot collection of samples in ostomates

  Current Status: Open

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• Expanded Access Program to Treat Patients With Previously Treated Metastatic Pancreatic Adenocarcinoma With Daraxonrasib

  Current Status: Open

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• PCCE Clinical Data and Specimen Repository for Malignant and Non-Malignant Diseases of the Pancreas

  Current Status: Open

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• A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)

  Current Status: Open

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• Targeted Agent and Profiling Utilization Registry (TAPUR) Study

  Current Status: Open

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• A Phase III, Double-blind, Randomized Study of Zolbetuximab in Combination With Pembrolizumab and Chemotherapy (CAPOX or mFOLFOX6) in First-line Treatment of Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma in Participants Whose Tumors Are HER2-negative, Claudin (CLDN) 18.2-positive and Programmed Death-ligand 1 (PD-L1)-Positive

  Current Status: Open

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• A Phase III, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 Versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)

  Current Status: Open

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• Establishment of a national biorepository to advance studies of immune-related adverse events

  Current Status: Open

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• TIGeR-PaC: Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine plus Nab-Paclitaxel following Induction with sequential IV Gemcitabine plus Nab-Paclitaxel and Radiotherapy for Unresectable Locally Advanced Pancreatic Cancer

  Current Status: Open

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• A Phase II/III, Multicenter, Randomized Open-Label Study of Zanzalintinib vs Everolimus in Participants With Previously Treated, Unresectable, Locally Advanced or Metastatic Neuroendocrine Tumors

  Current Status: Open

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• A Phase IIb/III, Randomized, Double-blind Study to Investigate the Efficacy, Safety, and Tolerability of Ponsegromab (PF-06946860 Compared With Placebo Both With Background First-Line Chemotherapy in Adult Participants With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

  Current Status: Open

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• A Randomized Study Evaluating GLIADEL Compared to Stereotactic Radiosurgery in Patients with Metastatic Brain Disease

  Current Status: Open

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• An Observational Study Associating Adiponectin Signaling with Acute and Chronic Toxicity Following Pelvic Radiation

  Current Status: Open

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