Using Ultrafast Ultrasound Elastography and Pulse Wave Velocity to Detect Myocardial and Arterial Stiffness as Early Signs of Cardiovascular Dysfunction in Childhood Cancer Survivors
Categories (click each to see list of all clinical trials associated with that category): Child Health Research Institute (CHRIONC), Pediatric (PEDONC)
Current Status: Open
Phase: N/A
Principal Investigator: Li, Ling
Contact Information:
Anupriya (Priya) Bhatnagar
pbhatnagar@unmc.edu
Summary
To investigate myocardial and arterial stiffness in childhood cancer survivors using advanced non-invasive imaging techniques. This study aims to:
- Evaluate myocardial stiffness using ultrafast ultrasound elastography.
- Assess arterial stiffness through pulse wave velocity (PWV) measurements.
- Determine the association between cumulative anthracycline dose and myocardial/arterial stiffness.
- Explore the impact of radiation therapy on myocardial/arterial stiffness.
The goal is to enhance early detection and understanding of cardiovascular dysfunction in this vulnerable population, ultimately improving long-term cardiovascular health outcomes.