Indication for Transplant

Criteria have been established to help determine if a patient is a candidate for transplantation. The criteria explain the reasons for inclusion in, or exclusion from, pancreas and/or kidney transplantation.


Criteria for pancreas transplantation:

  • Patients must have diabetes and early complications of the disease and/or hypoglycemia unawareness (insulin reactions) that have not responded to other medical treatments.
  • Patients must have adequate kidney function to tolerate the anti-rejection medications needed after transplant.
  • Patients must qualify for and be able to tolerate major surgery.
  • Patients and their family members/support system must be able to understand the risks and benefits of transplantation, including the long-term need for close medical follow-up and life-long need for anti-rejection therapy.
  • Patients/families must be able to accept the responsibility to be involved in the long-term care required after transplantation, including the financial responsibilities.


Factors and considerations that may result in exclusion from transplantation include:

  • The presence of some other life-threatening disease or condition that would not improve with transplantation. This would include certain cancers, infections that cannot be treated or cured or severe, uncorrectable heart disease.
  • History of chronic noncompliance including, but not limited to, medical treatments, medications or other behaviors that would affect the patient's ability to fully care for himself/herself after transplantation.
  • History of chronic and ongoing drug and/or alcohol abuse that cannot be successfully treated before transplantation, putting the patient at risk for continued harmful behavior after transplantation.
  • History of serious psychiatric disorders that cannot be successfully treated before transplantation and that would be considered a high risk for ongoing or increased severity of the psychiatric disorder after transplantation.
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