The Nebraska Medical Center participates
in a variety of clinical trials to test new, investigational
drugs and to study new ways of using known treatments. By researching
the latest and most innovative procedures and therapies, we can
provide patients access to the newest treatments. Building on
The Nebraska Medical Center’s strong traditions in transplant
and liver disease research, The Lied Transplant Center facilitates
basic and clinical research by encouraging greater interaction
among researchers and healthcare providers. This creates a unique
atmosphere for greater collaboration, discovery and application
of new knowledge.
Once a patient has been evaluated and approved
for a transplant, they may be eligible for participation in a clinical
trial. The following is a list of trials in progress.
Clinical Research Trials
“Studies of Inflammation, Infection
and Rejection in Intestinal Transplant Tissue.” (No external
funding)
This study is seeking to identify a way to
differentiate infection and rejection in an intestinal graft without
having to biopsy that tissue.
“An Open-Label Evaluation of the
Long-Term Efficacy and Safety of a Standardized Regimen of Growth
Hormone, Glutamine and a Modified Diet in the Treatment of Patients
with Short Bowel Syndrome.” (Lilly)
This protocol studies the effectiveness of
growth hormone used with glutamine and a modified diet to allow
patients with short bowel syndrome to reduce or eliminate their
dependence on intravenous nutrition (TPN).
“Identification of the Gene Defect
Causing Microvillus Atrophy.” (No external funding)
This is a study of a very rare disease that
is apparently linked to a genetic defect.
“A Prospective Study of Cell-Mediated
Immunity to Varicella (Chicken Pox) Following Vaccination with
Live Attenuated Varicella Virus (Varivax®) After Liver, Small
Intestine, or Combined Liver/Small Intestine Transplantation.” (No
external funding)
This study is examining the safety and effectiveness
of providing chicken pox vaccinations for patients who have received
liver and/or small intestine transplants.
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